Biomedical engineering projects encourage students to apply the principles of medicine and engineering for creating any methodology to solve problems and issues existing in the medical and pharmaceutical fields. Using various types of data acquisition system, students will learn how to design experiment, implement and summarize data for various science fairs and publication.
With the advent of the uncountable number of new technologies, in fact, more people has experiencing cases of nerve cord injuries. However, not an optimal animal model for nerve cord injuries has been documented using invertebrates. The study was designed to investigate the use of L. terrestris as a model for the treatment of spinal cord injuries and their follow-up monitoring. Using a telemetric system to record data, the pharmacological effects on action potential were assessed, while comparing with a negative control water on the waveforms. The impulse reactions of the earthworm were examined to varying voltages of electrical stimuli.
By comparing the Fast Fourier Transform, interpolation-foldagram and stabilization time from each waveform, it was suggested that the four drugs, Ibuprofen, Phenol, Benzocaine and Acetaminophen in this study had a characteristic trend in change of each parameter. According to the patterns derived from the waveforms, both the type and the amount of the substances had an effect on L. terrestris’ action potentials, though not statistically significant. The result showed that the parameters we measured could be proportional to the doses of drugs within a certain range of electric stimulation. This study might contribute to a more in-depth understanding of action potential propagation and nerve cord injury if it could be applied properly.
For other projects, designs of the smart chair, blind house, and stimulation/response metering system are under investigation. Jump right in!